Akt Inhibitors

Akt

Akt1

Akt2

Akt3

Akt Inducers, Inhibitors, Agonists & Activators

Product Name	Akt	Akt1	Akt2	Akt3	Purity
MK-2206 dihydrochloride			Akt2, IC₅₀: 12 nM	Akt3, IC₅₀: 65 nM	99.99%
Capivasertib			Akt2, IC₅₀: 7 nM	Akt3, IC₅₀: 7 nM	99.95%
Ipatasertib			Akt2, IC₅₀: 18 nM	Akt3, IC₅₀: 8 nM	99.88%
AKT inhibitor VIII			Akt2, IC₅₀: 210 nM	Akt3, IC₅₀: 2119 nM	98.97%
Oridonin			Akt2, IC₅₀: 8.9 μM		99.89%
GSK-690693			Akt2, IC₅₀: 13 nM	Akt3, IC₅₀: 9 nM	99.03%
Miransertib			Akt2, IC₅₀: 14 nM	Akt3, IC₅₀: 8.1 nM	99.32%
Afuresertib			Akt2, Ki: 2 nM	Akt3, Ki: 2.6 nM	99.53%
Thymoquinone	Akt				99.80%
Uprosertib			Akt2, IC₅₀: 328 nM	Akt3, IC₅₀: 38 nM	99.93%
Triciribine	Akt, IC₅₀: 130 nM (cell assay)				99.81%
BAY1125976			Akt2, IC₅₀: 18 nM (at 10 μM ATP)	Akt3, IC₅₀: 427 nM (at 10 μM ATP)	99.52%
Rizavasertib			Akt2, Ki: 160 pM	Akt3, Ki: 160 pM	99.71%
LM22B-10	Akt				99.92%
Ipatasertib dihydrochloride			Akt2, IC₅₀: 18 nM	Akt3, IC₅₀: 8 nM	99.27%
MK-2206		Akt1, IC₅₀: 8 nM	Akt2, IC₅₀: 12 nM	Akt3, IC₅₀: 65 nM	99.72%
INY-03-041			Akt2, IC₅₀: 6.8 nM	Akt3, IC₅₀: 3.5 nM	99.74%
AT7867			Akt2, IC₅₀: 17 nM	Akt3, IC₅₀: 47 nM	99.88%
Engasertib			Akt2, IC₅₀: 0.09 μM	Akt3, IC₅₀: 2.75 μM	99.65%
AT13148			Akt2, IC₅₀: 402 nM	Akt3, IC₅₀: 50 nM	99.20%
CCT128930			Akt2, IC₅₀: 6 nM		99.69%
H-Ile-Lys-Val-Ala-Val-OH	Akt				99.42%
M2698				Akt3, IC₅₀: 1 nM	99.87%
Serplulimab		Akt1	Akt2	Akt3	99.30%
Afuresertib hydrochloride			Akt2, Ki: 2 nM	Akt3, Ki: 2.6 nM	99.95%
Vevorisertib trihydrochloride			Akt2, IC₅₀: 0.81 nM	Akt3, IC₅₀: 1.31 nM	99.13%
Pifusertib hydrochloride			Akt2, IC₅₀: 1.6 nM	Akt3, IC₅₀: 44 nM
MS170			Akt2, Kd: 77 nM	Akt3, Kd: 6.5 nM	99.72%
Phellopterin	Akt				99.94%
AT7867 dihydrochloride			Akt2, IC₅₀: 17 nM	Akt3, IC₅₀: 47 nM	99.75%
AT-533	Akt				98.38%
Akt1/Akt2-IN-1			Akt2, IC₅₀: 42 nM		99.30%
4-Methylbenzylidene camphor	Akt				99.87%
Miransertib hydrochloride			Akt2, IC₅₀: 174 nM	Akt3, IC₅₀: 8.1 nM	99.74%
AKT-IN-6			Akt2	Akt3	99.08%
Deltonin	Akt				99.94%
3CAI			Akt2		98.32%
20(R)-Ginsenoside Rh2		Akt1			≥98.0%
Hu7691			Akt2, IC₅₀: 97.5 nM	Akt3, IC₅₀: 28 nM	99.91%
CCT128930 hydrochloride			Akt2, IC₅₀: 6 nM		98.97%
INY-03-041 trihydrochloride		Akt1, IC₅₀: 2.0 nM	Akt2, IC₅₀: 6.8 nM	Akt3, IC₅₀: 3.5 nM	99.27%
Isoprocurcumenol	Akt
AKT-IN-3			Akt2, IC₅₀: 1.2 nM	Akt3, IC₅₀: 1.7 nM	99.29%
PTP1B-IN-24	Akt, IC₅₀: 1.4 μM
Vevorisertib			Akt2, IC₅₀: 0.81 nM	Akt3, IC₅₀: 1.31 nM	98.03%
Akt1/Akt2-IN-2		Akt1, IC₅₀: 138 nM	Akt2, IC₅₀: 212 nM	Akt3, IC₅₀: 7.2 mM	98.57%
MS15			Akt2, IC₅₀: 90 ± 2.8 nM	Akt3, IC₅₀: 544 ± 2.9 nM
Akt1&PKA-IN-2		Akt1, IC₅₀: 0.007 μM
Coelonin	Akt				≥98.0%
Rhodiolin	Akt
TRPM7-IN-1	Akt				98.83%
AKT1-IN-9		AKT1(E17K)
Pifusertib			Akt2, IC₅₀: 1.6 nM	Akt3, IC₅₀: 44 nM	98.74%
Akt1&PKA-IN-1	Akt, IC₅₀: 0.11 μM
MS98			Akt2, : 140 nM	Akt3, : 8.1 nM
Hu7691 free base			Akt2, IC₅₀: 97.5 nM	Akt3, IC₅₀: 28 nM
MK-2206 free base			Akt2, IC₅₀: 12 nM	Akt3, IC₅₀: 65 nM
AKT-IN-8			Akt2, IC₅₀: 2.44 nM	Akt3, IC₅₀: 9.47 nM
AKT-IN-13			Akt2, IC₅₀: 2.4 nM	Akt3, IC₅₀: 0.3 nM
AKT-IN-18	Akt, IC₅₀: 69.45 μM
Akt1-IN-5		Akt1, IC₅₀: <15 nM
Akt1-IN-4		Akt1
PROTAC PI3K/110β degrader-2	Akt
Anti-Mouse E-Cadherin/CD324 Antibody (DECMA-1)	Akt
AKT-IN-28	Akt, Kd: 2.07 μM
Ipatasertib tosylate		Akt1, IC₅₀: 5 nM	Akt2, IC₅₀: 18 nM	Akt3, IC₅₀: 8 nM
Gamendazole		Akt1			99.44%
Eudebeiolide B	Akt
Akt1-IN-6		Akt1, IC₅₀: <15 nM
Tanshinol borneol ester	Akt
AKT-IN-5			Akt2, IC₅₀: 400 nM
Akt1-IN-7		Akt1, IC₅₀: <15 nM
Akt1-IN-8		Akt1, IC₅₀: 8.8 nM
Rac-ZINC4085554		Akt1
PD-1/PD-L1-IN-54	Akt
Akt1-IN-2		Akt1, IC₅₀: 4.6 μM	Akt2, IC₅₀: >250 μM	Akt3, IC₅₀: >250 μM
Uprosertib hydrochloride			Akt2, IC₅₀: 328 nM	Akt3, IC₅₀: 38 nM

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