2. Metabolic Enzyme/Protease Apoptosis
  3. Ser/Thr Protease Apoptosis
  4. AAF-CMK

AAF-CMK 是一种 TPPII (tripeptidylpeptidase II) 抑制剂，其具有抗肿瘤活性并可诱导细胞凋亡。AAF-CMK 可用于白血病的研究。

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Custom Peptide Synthesis

AAF-CMK Chemical Structure

AAF-CMK Chemical Structure

CAS No. : 102129-66-8

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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Customer Review

AAF-CMK 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AAF-CMK is a TPPII (tripeptidylpeptidase II) inhibitor, shows anti-tumor activity and induces apoptosis. AAF-CMK can be used in leukemia research[1].

体外研究
(In Vitro)

AAF-CMK (0-20 μM; 24 h) shows potentiated antitumor effects of U937 leukemia cells in combination with TRAIL or TNF[1].
AAF-CMK (20 μM; 24 h) increases TNF- and TRAIL-induced U937 cell apoptosis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AAF-CMK 相关抗体:

Cell Viability Assay[1]

Cell Line: U937 human promonocytic leukemia cells
Concentration: 0-20 μM
Incubation Time: 24 h
Result: Resulted in the potentiation of growth inhibitory cytostatic effects of TRAIL as well as TNF.

Apoptosis Analysis[1]

Cell Line: U937 human promonocytic leukemia cells
Concentration: 20 μM
Incubation Time: 24 h
Result: Increased the percentage of apoptotic cells to 55.8% in combination with TRAIL.
Increased number of cells with characteristic apoptotic morphology in groups treated with AAF-CMK and both TRAIL or TNF compared to each group treated alone.
分子量

339.82

Formula

C16H22ClN3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AAF-CMK 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AAF-CMK102129-66-8Ser/Thr ProteaseApoptosisSerine proteasesSerine endopeptidasesThreonine proteasesanti-tumor activityinduce apoptosisleukemiaInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-129407A
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