2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. AFM24

AFM24 是 CHO 表达的、具有 TandAb 结构的双特异性抗体，靶向 EGFR&Fc-gamma-RIIIA。AFM24 带有 huIgG1-SCFV 型重链和 λ 型轻链，其预测的分子量 (MW) 为 74.5 kDa。AFM24 的同型对照可参考 Human IgG1 kappa, Isotype Control (HY-P99001)。

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规格 价格 是否有货 数量
1 mg ￥3500
In-stock
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AFM24 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

生物活性

AFM24 is a bispecific antibody with a TandAb structure expressed in CHO, targeting EGFR&Fc-gamma-RIIIA. AFM24 contains a huIgG1-SCFV heavy chain and a λ light chain, with a predicted molecular weight (MW) of 74.5 kDa. The isotype control for AFM24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

同型

Human IgG1 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

EGFR & Fc-gamma-RIIIA
Clinical Trial
基因 ID

1956  [NCBI] & 2214  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

196.34 kDa

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized Fc gamma RIIA/CD32a Protein, Human can bind AFM24. The EC50 for this effect is 93.45 ng/mL.
  • Immobilized EGFR Protein, Human can bind AFM24. The EC50 for this effect is 86.89 ng/mL.
纯度 & 产品资料

AFM24 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AFM24AFM 24AFM-24EGFREpidermal growth factor receptorErbB-1HER1Bispecific AntibodyEGFR & Fc-gamma-RIIIA AntibodyInhibitorinhibitorinhibit

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Inquiry Information

产品名称：
AFM24
目录号：
HY-P990314
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