2. GPCR/G Protein
  3. Protease Activated Receptor (PAR)
  4. Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA 

目录号: HY-P5372A
产品使用指南 技术支持

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA 是一种生物活性肽，是一种选择性蛋白酶激活受体 1 (PAR-1) 激动剂，其对 PAR-1 的特异性高于 PAR-2。PAR-1 属于 G 蛋白偶联受体亚家族，已知可介导凝血酶的细胞作用。除了凝血酶的多种细胞作用外，PAR-1 还被证明可以与 PAR-4 协调并调节凝血酶诱导的肝细胞癌，该肝细胞癌在肿瘤环境中形成凝血酶，被归类为“凝血型”。

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Custom Peptide Synthesis

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥425
In-stock
5 mg ￥1062
In-stock
10 mg ￥1700
In-stock
25 mg ￥2805
In-stock
50 mg ￥4250
In-stock
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA:

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA 相关抗体

Top Publications Citing Use of Products

查看 Protease Activated Receptor (PAR) 亚型特异性产品:

查看所有亚型
PAR1 PAR2 PAR4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'[1].

IC50 & Target[1]

PAR1

 

分子量

883.02 (free base)

Formula

C42H63FN12O8.xC2HF3O2
性状

固体

Sequence

Ala-{Phe(p-Fluoro)}-Arg-{Cha}-{Cit}-Tyr-NH2
Sequence Shortening

A-{Phe(p-Fluoro)}-R-{Cha}-{Cit}-Y-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2Protease Activated Receptor (PAR)Thrombin receptorsBioactive peptideProtease activating receptor 1PAR-1AgonistThrombinHepatocellular carcinomaInhibitorinhibitorinhibit

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