2. Anti-infection
  3. CHIKV Flavivirus
  4. Anti-Chikungunya virus E2 Antibody (CHK-265)

Anti-Chikungunya virus E2 Antibody (CHK-265) 

目录号: HY-P990825 纯度: 95%
COA 技术支持

Anti-Chikungunya virus E2 Antibody (CHK-265) 是小鼠源 IgG2c κ 型抗体抑制剂，靶向 Chikungunya virus E2。Anti-Chikungunya virus E2 Antibody (CHK-265) 与基孔肯雅病毒 E2 糖蛋白 B 结构域上的一个保守表位发生反应。Anti-Chikungunya virus E2 Antibody (CHK-265) 可阻断病毒的进入和释放。Anti-Chikungunya virus E2 Antibody (CHK-265) 可用于感染性疾病的研究，如基孔肯雅病毒 (CHIKV)、马亚罗病毒 (MAYV) 和奥尼昂尼昂病毒 (ONNV)。

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Anti-Chikungunya virus E2 Antibody (CHK-265)

Anti-Chikungunya virus E2 Antibody (CHK-265) Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

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规格 价格 是否有货 数量
1 mg ￥2000
In-stock
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10 mg 现货 询价
50 mg   询价  
100 mg   询价  

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Anti-Chikungunya virus E2 Antibody (CHK-265) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Chikungunya virus E2 Antibody (CHK-265) is mouse-derived IgG2c κ type antibody inhibitor, targeting to Chikungunya virus E2. Anti-Chikungunya virus E2 Antibody (CHK-265) reacts with a conserved epitope on the B domain of the E2 glycoprotein of chikungunya virus. Anti-Chikungunya virus E2 Antibody (CHK-265) can block viral entry and egress. Anti-Chikungunya virus E2 Antibody (CHK-265) can be used for the research of infection, such as Chikungunya virus (CHIKV), Mayaro (MAYV) and O’nyong’nyong virus (ONNV)[1].

同型

Mouse IgG2c
推荐同型对照抗体
反应种属

Virus
IC50 & Target

B domain of the E2 glycoprotein of chikungunya virus
体外研究
(In Vitro)

Anti-Chikungunya virus E2 Antibody (CHK-265) (0.001-10 μg/mL, 19 h) 可中和与基孔肯雅病毒 (CHIKV) 亲缘关系近的甲病毒 (奥尼昂尼昂病毒，ONNV) 或远的 (马亚罗病毒，MAYV；罗斯河病毒，RRV；以及辛德毕斯病毒，SFV)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Chikungunya virus E2 Antibody (CHK-265) 相关抗体:
体内研究
(In Vivo)

Anti-Chikungunya virus E2 Antibody (CHK-265) (100 μg，腹腔注射，感染前 1 天给药) 可保护感染基孔肯雅病毒 (CHIKV)/马亚罗病毒 (MAYV)/奥尼昂尼昂病毒(ONNV) 的小鼠免受甲病毒疾病侵害[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CHIKV/MAYV/ONNV infected mice models[1]
Dosage: 100 μg
Administration: Intraperitoneally injection, 1 day prior to infection
Result: Reduced ankle joint swelling.
Reduced spread to the contralateral ankle joint.
Decreased viral burden.
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Chikungunya virus E2 Antibody (CHK-265) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Chikungunya virus E2 Antibody (CHK-265)CHIKVFlavivirusChikungunya virus AlphavirusesChikungunya virusMayaroO’nyong’nyong virusInhibitorinhibitorinhibit

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目录号：
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