2. Apoptosis
  3. Apoptosis
  4. Anti-melanoma agent 1

Anti-melanoma agent 1 (Compound 5m) 是一种抗黑素瘤剂，可诱导细胞凋亡（apoptosis）。

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Anti-melanoma agent 1 Chemical Structure

Anti-melanoma agent 1 Chemical Structure

CAS No. : 2418579-17-4

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Anti-melanoma agent 1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent and induces cell apoptosis[1].

体外研究
(In Vitro)

Anti-melanoma agent 1 (Compound 5m) (0-100 μM, 48 h) shows antiproliferative activity against melanoma cells[1].
Anti-melanoma agent 1 (0-10 μM) inhibits colony formation in SK-MEL-28[1].
Anti-melanoma agent 1 (1 and 2 μM) induces cell apoptosis (24 h), arrests cell cycle at G2/M phase (12 h), inhibits cell migration (48 h) and disrupts the cellular microtubule network[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-melanoma agent 1 相关抗体:

Cell Proliferation Assay[1]

Cell Line: SK-MEL-5, SK-MEL-28 and A375
Concentration: 0-100 μM
Incubation Time: 48 h
Result: Showed antiproliferative activity with IC50 values of 3.70 ± 0.17, 3.30 ± 0.06 and 1.98 ± 0.10 μM against SK-MEL-5, SK-MEL-28 and A375 cells, respectively.

Apoptosis Analysis[1]

Cell Line: SK-MEL-28
Concentration: 1 μM and 2 μM
Incubation Time: 24 h
Result: Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line: SK-MEL-28
Concentration: 1 μM and 2 μM
Incubation Time: 12 h
Result: Arrested cell cycle at G2/M phase.

Cell Migration Assay [1]

Cell Line: SK-MEL-28
Concentration: 1 μM and 2 μM
Incubation Time: 48 h
Result: Inhibited cell migration.
分子量

424.53

Formula

C28H28N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-melanoma agent 1 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-melanoma agent 12418579-17-4ApoptosisSK-MEL-28anti-melanomapropranololInhibitorinhibitorinhibit

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目录号：
HY-150534
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