1. Anti-infection GPCR/G Protein
  2. HIV Apelin Receptor (APJ)
  3. Apelin-36(rat, mouse) TFA

Apelin-36(rat, mouse) TFA 是一种内源性孤儿 G 蛋白偶联受体 APJ 激动剂。Apelin-36(rat, mouse) TFA 与 APJ 受体结合,IC50 为 5.4 nM,显著抑制 cAMP 的产生,EC50 为 0.52 nM。Apelin-36(rat, mouse) TFA 阻断 HIV-1HIV-2 毒株进入表达 APJ 的 NP-2/CD4 细胞。

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Custom Peptide Synthesis

Apelin-36(rat, mouse) TFA Chemical Structure

Apelin-36(rat, mouse) TFA Chemical Structure

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Apelin-36(rat, mouse) TFA 的其他形式现货产品:

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-36(rat, mouse) TFA binds to APJ receptors with an IC50 of 5.4 nM, and potently inhibits cAMP production with an EC50 of 0.52 nM. Apelin-36(rat, mouse) TFA blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ[1][2].

IC50 & Target[1]

HIV-1

 

HIV-2

 

分子量

4314.91

Formula

C187H305F3N68O45S

Sequence

Leu-Val-Lys-Pro-Arg-Thr-Ser-Arg-Thr-Gly-Pro-Gly-Ala-Trp-Gln-Gly-Gly-Arg-Arg-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Sequence Shortening

LVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Apelin-36(rat, mouse) TFA 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Apelin-36(rat, mouse) TFA
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HY-P1065A
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