2. Others PI3K/Akt/mTOR Stem Cell/Wnt
  3. Biochemical Assay Reagents GSK-3
  4. AZ12943203

AZ12943203 (Compound 13e) 是一种 GSK-3 PET 放射性配体，Kd 为 2.94 nM。AZ12943203 对 GSK-3β 具有显著的抑制效力 (IC50 ：4.44 nM)，并且可以特异性结合啮齿动物脑中富含 GSK-3 的区域。AZ12943203 可用于神经退行性疾病成像，尤其是阿尔茨海默病。

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AZ12943203

AZ12943203 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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AZ12943203 相关抗体

Top Publications Citing Use of Products

查看 GSK-3 亚型特异性产品:

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GSK-3 GSK-3α GSK-3β

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZ12943203 (Compound 13e) is a GSK-3 PET radioligand with a Kd of 2.94  nM. AZ12943203 has a significant inhibitory potency toward GSK-3β (IC50 : 4.44 nM), and can specifically bind to GSK-3-rich regions of the rodent brain. AZ12943203 can be used for neurodegenerative diseases imaging, particularly Alzheimer’s disease[1].

分子量

493.58

Formula

C26H32FN7O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AZ12943203 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ12943203AZ 12943203AZ-12943203Biochemical Assay ReagentsGSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3PETRadioligandAlzheimer’s diseaseInhibitorinhibitorinhibit

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产品名称：
AZ12943203
目录号：
HY-174923
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