2. Metabolic Enzyme/Protease
  3. Proteasome
  4. Biotin-(Oaa)3-epoxomicin

Biotin-(Oaa)3-epoxomicin (Compound 13) 是 Epoxomicin (HY-13821) 的生物素化活性形式。Biotin-(Oaa)3-epoxomicin 是一种靶向蛋白酶体 (Proteasome) 的高亲和力探针。Biotin-(Oaa)3-epoxomicin 可与多个蛋白酶体催化亚基 (如 LMP7、Z 和 MECL1) 共价结合。

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Custom Peptide Synthesis

Biotin-(Oaa)3-epoxomicin

Biotin-(Oaa)3-epoxomicin Chemical Structure

CAS No. : 247068-92-4

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Biotin-(Oaa)3-epoxomicin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Biotin-(Oaa)3-epoxomicin (Compound 13) is a biotinylated active form of Epoxomicin (HY-13821). Biotin-(Oaa)3-epoxomicin is a high affinity probe targeting Proteasome. Biotin-(Oaa)3-epoxomicin covalently binds to multiple proteasome catalytic subunits (such as LMP7, Z and MECL1)[1].

分子量

1078.45

Formula

C54H95N9O11S
CAS 号
Sequence

Biotin-{Oaa}-{Oaa}-{Oaa}-Ile-Ile-Thr-{Leu((2R)-2-methyloxiranyl)}
Sequence Shortening

Biotin-{Oaa}-{Oaa}-{Oaa}-IIT-{Leu((2R)-2-methyloxiranyl)}
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Biotin-(Oaa)3-epoxomicin 相关分类

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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotin-(Oaa)3-epoxomicin247068-92-4ProteasomeBiotinylatedEpoxomicinAffinity probeLMP7ZMECL1Inhibitorinhibitorinhibit

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