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  3. BMS-986325 (anti-CD40)

BMS-986325 (anti-CD40) 

目录号: HY-P990111 纯度: 96.46%
COA 技术支持

BMS-986325 (anti-CD40) 是一种 CD40 抑制剂,可用于原发性干燥综合征研究。

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg 现货 询价
10 mg   询价  
50 mg   询价  

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMS-986325 (anti-CD40) is a CD40 inhibitor, and can be used for primary Sj gren's syndrome research[1].

同型

Human IgG1 kappa

推荐同型对照抗体
反应种属

Human

IC50 & Target

CD40

体内研究
(In Vivo)

BMS-986325 (1 和 10 mg/kg,静脉注射,小鼠) 显示出 0.5-1.02 mL/d/kg 的低总血清清除率,有限的稳态分布容积 “Vss” 为 0.12 至 0.19 L/kg,且长效 表观消除半衰期为 118 至 183 h[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

基因 ID

958  [NCBI]

Accession

P25942-1

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

144.92 kDa

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Biological Activity
  • Immobilized CD40 Protein, Human (HEK293, His, HY-P73499A) can bind BMS-986325 (anti-CD40). The EC50 for this effect is 6.675 ng/mL.
纯度 & 产品资料

纯度: 96.46%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
BMS-986325 (anti-CD40)
目录号:
HY-P990111
需求量: