1. Anti-infection
  2. Virus Protease SARS-CoV
  3. CIM-834

CIM-834 是一种具有口服活性和选择性抑制剂,靶向冠状病毒膜蛋白 (M protein),对 SARS-CoV-2SARS-CoV 具有强效的病毒组装抑制活性。CIM-834 以非共价方式结合 M 蛋白的短形式 (Mshort),稳定 Mshort,并阻止其构象转换为病毒粒子组装所需的长形式 (Mlong),从而抑制病毒颗粒的形成。CIM-834 有望用于 COVID-19 和其他冠状病毒感染的研究

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CIM-834

CIM-834 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥2070
10 - 12 周
5 mg ¥4560
10 - 12 周
10 mg 询价 10 - 12 周
25 mg 询价 10 - 12 周
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CIM-834 is an orally active and selective inhibitor targeting the coronavirus membrane protein (M protein), which potently blocks viral assembly against SARS-CoV-2 and SARS-CoV. CIM-834 binds to the short form of the M protein (Mshort) in a non-covalent manner, stabilizing Mshort and preventing its conformational switch to the long form (Mlong) required for virion assembly, thereby inhibiting viral particle formation. CIM-834 is promising for research of COVID-19 and other coronavirus infections[1].

分子量

494.68

Formula

C27H42N8O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
CIM-834
目录号:
HY-172760
需求量: