2. PI3K/Akt/mTOR Apoptosis
  3. Akt MDM-2/p53
  4. cis,trans-Germacrone

cis,trans-Germacrone 是 Germacrone (HY-N0440) 的异构体。Germacrone 具有广泛的抗肿瘤、抗氧化和抗炎作用。Germacrone 抑制肺癌细胞增殖并改变 Akt/MDM2/p53。Germacrone 还能在 G1/S 期阻滞细胞周期。

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cis,trans-Germacrone Chemical Structure

cis,trans-Germacrone Chemical Structure

CAS No. : 32663-51-7

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cis,trans-Germacrone 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1].

分子量

218.33

Formula

C15H22O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

cis,trans-Germacrone 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis,trans-Germacrone32663-51-7AktMDM-2/p53PKBProtein kinase BInhibitorinhibitorinhibit

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