2. Anti-infection
  3. Bacterial
  4. Competence-Stimulating Peptide-2 (CSP-2)

Competence-Stimulating Peptide-2 (CSP-2) 

目录号: HY-P2522 纯度: 98.56%
COA 产品使用指南 技术支持

Competence-Stimulating Peptide-2 (CSP-2) 是 Streptococcus pneumoniae 产生的一种 17 个氨基酸信号肽，对其兼容受体 ComD2 的 EC50 为 50.7 nM。Competence-Stimulating Peptide-2 (CSP-2) 可通过群体感应调控细菌的感受态形成、毒力和生物膜形成等表型。

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Custom Peptide Synthesis

Competence-Stimulating Peptide-2 (CSP-2)

Competence-Stimulating Peptide-2 (CSP-2) Chemical Structure

CAS No. : 1174553-84-4

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Competence-Stimulating Peptide-2 (CSP-2) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid signal peptide produced by Streptococcus pneumoniae, with an EC50 of 50.7 nM for its compatible receptor ComD2. Competence-Stimulating Peptide-2 (CSP-2) can regulate bacterial phenotypes such as competence development, virulence, and biofilm formation through quorum sensing[1][2].

体外研究
(In Vitro)

Competence-Stimulating Peptide-2 (CSP-2) 与 CSP1 (HY-P2454) 共同作用可诱导 NESp 菌株 MNZ41 形成感受态，使其能摄取外源 DNA 并发生转化[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Competence-Stimulating Peptide-2 (CSP-2) 相关抗体:
分子量

2178.69

Formula

C101H172N28O23S
CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

EMRISRIILDFLFLRKK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Stored under nitrogen, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
细胞实验： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Competence-Stimulating Peptide-2 (CSP-2) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Competence-Stimulating Peptide-2 (CSP-2)1174553-84-4BacterialQuorumsensingsignalpeptideComD2Inhibitorinhibitorinhibit

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