2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. µ-Conotoxin KIIIA

μ-Conotoxin KIIIA 是一种镇痛的 μ-芋螺毒素，可从 Conus kinoshitai 中分离出来。μ-Conotoxin KIIIA 阻断哺乳动物神经元电压门控钠通道 (VGSC) (Nav1.2)。μ-Conotoxin KIIIA 可用于疼痛研究。

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µ-Conotoxin KIIIA Chemical Structure

µ-Conotoxin KIIIA Chemical Structure

CAS No. : 884469-67-4

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规格 是否有货
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µ-Conotoxin KIIIA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

μ-Conotoxin KIIIA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2).μ-Conotoxin KIIIA can be used for research of pain[1][2].

IC50 & Target

NaV1.2 Channel[2]
分子量

1884.16

Formula

C70H106N28O22S6
CAS 号
Sequence

Cys-Cys-Asn-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ser-Arg-Cys-Cys-NH2 (Disulfide bonds：Cys1-Cys9,Cys2-Cys15,Cys4-Cys16)
Sequence Shortening

CCNCSSKWCRDHSRCC-NH2 (Disulfide bonds：Cys1-Cys9,Cys2-Cys15,Cys4-Cys16)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

µ-Conotoxin KIIIA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

µ-Conotoxin KIIIA884469-67-4Sodium ChannelNa channelsNa+ channelsConotoxintoxinneuronalpainanalgesicInhibitorinhibitorinhibit

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目录号：
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