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  4. D,L-erythro-PDMP

D,L-erythro-PDMP 是 PDMP 的赤型异构体。D,L-erythro-PDMP 诱导体外兔皮肤成纤维细胞的生长抑制。PDMP 是一种 UDP 葡萄糖神经酰胺葡萄糖基转移酶抑制剂。

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D,L-erythro-PDMP Chemical Structure

D,L-erythro-PDMP Chemical Structure

CAS No. : 109760-77-2

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D,L-erythro-PDMP 的其他形式现货产品:

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D,L-erythro-PDMP 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

D,L-erythro-PDMP is an erythro isomer of PDMP. D,L-erythro-PDMP causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2].

体外研究
(In Vitro)

D,L-erythro-PDMP (0, 12, 25, 50 μM; 0, 4, 7, 10 days) shows an inhibitory effect on cell growth of rabbit skin fibroblasts[1].
D,L-erythro PDMP (50 μM; 3 days) has cytotoxic of rabbit skin fibroblasts on cell morphology[1].
D,L-erythro-PDMP (40 μM; 24 h; MDCK cells) induces a marked increase in glucosyltransferase specific activity: 14.6 nmol/h per mg protein[2].
D,L-erythro-PDMP (40 μM; 6 h) protects the cells against loss of synthase in cells exposed to cycloheximide[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

D,L-erythro-PDMP 相关抗体:

Cell Proliferation Assay[1]

Cell Line: Rabbit skin fibroblast
Concentration: 0, 12, 25, 50 μM
Incubation Time: 0, 4, 7, 10 days
Result: Showed an inhibitory effect on cell growth.

Cell Cytotoxicity Assay[1]

Cell Line: Rabbit skin fibroblast
Concentration: 50 μM
Incubation Time: 3 days
Result: Had cytotoxic on cell morphology.
分子量

390.56

Formula

C23H38N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

D,L-erythro-PDMP 相关分类

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Keywords:

D,L-erythro-PDMP109760-77-2Othersgrowth inhibitionfibroblastsMDCKerythrod cellerythro isomerInhibitorinhibitorinhibit

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HY-116392G
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