2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. DAPI

DAPI  (Synonyms: 4',6-Diamidino-2-phenylindole)

目录号: HY-D2868
产品使用指南 技术支持

DAPI (Compound 3) 是一种酸敏感离子通道 3 (ASIC3) 抑制剂。DAPI 是通过与 ASIC3 结合，阻断通道功能。DAPI 可用于慢性疼痛治疗的研究。

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DAPI

DAPI Chemical Structure

CAS No. : 47165-04-8

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规格 价格 是否有货 数量
1 mg ￥1560
1 - 2 周
5 mg ￥3120
1 - 2 周
10 mg ￥5120
1 - 2 周
25 mg 询价 1 - 2 周
50 mg 询价 1 - 2 周
100 mg   询价  
200 mg   询价  

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Other Forms of DAPI:

DAPI 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 79 篇科研文献

IF

    DAPI purchased from MCE. Usage Cited in: Pharmaceuticals (Basel). 2022 Jun 6;15(6):721.

    The nuclei are counterstained with DAPI (10 μM) in the dark for 10 min at room temperature. Fluorescence is monitored using confocal microscope, and foci of phospho-H2A.X was quantified using ImageJ software.

    DAPI purchased from MCE. Usage Cited in: Acta Pharmacol Sin. 2021 Jul;42(7):1111-1123.  [Abstract]

    Mice intestine tissues sections were incubated with a TUNEL reaction mixture for 1 h at 37 °C in the dark. Next, the sections are stained with 0.1 μg/mL DAPI.

    DAPI purchased from MCE. Usage Cited in: Oncotargets Ther. 2020 Oct 6;13:9941-9952.  [Abstract]

    Human GC MGC-803 and NCI-N87 cells are seeded into 24-well plates with glass slide for 24h in RPMI-1640 medium. And 0.1% DAPI staining is performed against light for 30 minutes.

    DAPI purchased from MCE. Usage Cited in: Acta Biomater. 2019 Sep 15;96:468-479.  [Abstract]

    CLSM observations of tested Cy5-nanocomplexes incubated with RAW 264.7 macrophages show the fluorescent distributions of DAPI, nanocomplexes, and ROS (DCFH-DA) in the presence and absence NIR treatment.

    DAPI purchased from MCE. Usage Cited in: Phytomedicine. 2020 Mar;68:153146.  [Abstract]

    MC3T3-E1 cells incubated with 1 μg/ml DAPI dihydrochloride for 5 min and observed them under a fluorescence microscope. Effects of sweroside on ER-α and GPR30 expressions by immunofluorescence, white and yellow arrows mean target protein distribution in the cell nuclei and membrane, respectively.

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    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment[1].

    分子量

    277.32

    Formula

    C16H15N5
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    DAPI 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    DAPI47165-04-84',6-Diamidino-2-phenylindoleSodium ChannelNa channelsNa+ channelsASIC3painSD ratsCFAInhibitorinhibitorinhibit

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