2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  3. ADC Antibody CD38
  4. Daratumumab (PBS)

Daratumumab (PBS)  (Synonyms: Anti-Human CD38, Human Antibody (PBS))

目录号: HY-P9915A 纯度: ≥95.0%
COA

摩尔计算器

Daratumumab (PBS) (Anti-Human CD38) 是首创的特异性抗 CD38 单克隆抗体 (IgG1)。Daratumumab (PBS) 具有抗多发性骨髓瘤(MM) 的作用。Daratumumab (PBS) 损伤了 MM 细胞的粘附，从而增加了 MM 对蛋白酶体抑制的敏感性。

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Daratumumab (PBS) Chemical Structure

Daratumumab (PBS) Chemical Structure

CAS No. : 945721-28-8

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规格 价格 是否有货 数量
1 mg ￥1600
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5 mg ￥5600
In-stock
10 mg ￥9000
In-stock
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Customer Review

Other Forms of Daratumumab (PBS):

Daratumumab (PBS) 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Daratumumab (PBS) (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab (PBS) has anti-multiple myeloma (MM) effect. Daratumumab (PBS) impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition[1][2].

体外研究
(In Vitro)

Daratumumab（Anti-Human CD38）在表达 CD38 的淋巴瘤和 MM 衍生细胞系中诱导有效的 Ab 依赖性细胞毒性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Daratumumab (PBS) 相关抗体:
体内研究
(In Vivo)

Daratumumab（腹腔注射；0.5 mg/kg；Daudi-luc 细胞攻击后 14 天）可抑制小鼠异种移植肿瘤模型中表达 CD38 的肿瘤细胞的生长[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (151 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Daratumumab (PBS) 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Daratumumab (PBS)945721-28-8Anti-Human CD38, Human Antibody (PBS)ADC AntibodyCD38Inhibitorinhibitorinhibit

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