1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. DBCO-PEG3-SS-NHS ester

DBCO-PEG3-SS-NHS ester 是一种可降解 (cleavable) 的含 3 个单元 PEG 的 ADC linker,可用于合成抗体偶联活性分子 (ADC)。DBCO-PEG3-SS-NHS ester 是一种点击化学试剂。它含有 DBCO 基团,可以和含有 Azide 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。

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DBCO-PEG3-SS-NHS ester Chemical Structure

DBCO-PEG3-SS-NHS ester Chemical Structure

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     可免费申领三个不同产品的试用装。

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规格 是否有货
25 mg
询价

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-SS-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC50 & Target

Disulfide Cleavable Linker

 

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

697.82

Formula

C34H39N3O9S2

性状

油状物

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥90.0%

参考文献

DBCO-PEG3-SS-NHS ester 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DBCO-PEG3-SS-NHS ester
目录号:
HY-133431
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