2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. DBCO-Sulfo-NHS ester sodium

DBCO-Sulfo-NHS ester sodium 

目录号: HY-123687 纯度: ≥90.0%
COA 产品使用指南

摩尔计算器

DBCO-Sulfo-NHS ester sodium 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联活性分子 (ADCs) 的合成。DBCO-Sulfo-NHS ester (sodium) 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。

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DBCO-Sulfo-NHS ester sodium Chemical Structure

DBCO-Sulfo-NHS ester sodium Chemical Structure

CAS No. : 1400191-52-7

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5 mg ￥2300
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DBCO-Sulfo-NHS ester sodium 相关抗体

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查看 ADC Linker 亚型特异性产品:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC50 & Target[1]

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DBCO-Sulfo-NHS ester sodium 相关抗体:
分子量

532.50

Formula

C25H21N2NaO8S
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

DBCO-Sulfo-NHS ester sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DBCO-Sulfo-NHS ester1400191-52-7ADC LinkerAntibody-drug conjugates linkercleavableADCantibody-drugconjugatesInhibitorinhibitorinhibit

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目录号：
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