2. Metabolic Enzyme/Protease Anti-infection
  3. Dihydroorotate Dehydrogenase SARS-CoV
  4. DHODH-IN-31

DHODH-IN-31 是一种人二氢乳清酸脱氢酶 (DHODH) 抑制剂，其 IC50 值为 0.59 μM。DHODH-IN-31 具有抗病毒活性。DHODH-IN-31 可用于感染相关研究，如SARS-CoV-2。

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DHODH-IN-31

DHODH-IN-31 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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DHODH-IN-31 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DHODH-IN-31 is a human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.59 μM. DHODH-IN-31 exhibits antiviral activity. DHODH-IN-31 can be used for the research of infection, such as SARS-CoV-2[1].

IC50 & Target[1]

hDHODH

0.59 μM (IC50)

SARS-CoV-2

0.15 μM (EC50)

体外研究
(In Vitro)

DHODH-IN-31 (Compound 10e) 对 SARS-CoV-2 具有抗病毒活性， EC50 值为 0.15 μM[1]。
DHODH-IN-31 在 Vero 细胞和 SH-SY5Y 细胞中的 CC50 值分别为 26 μM 和 180 μM[1]。
DHODH-IN-31 (0.01-10 μM) 可抑制 Calu-3 细胞中 SARS-CoV-2 的病毒复制[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DHODH-IN-31 相关抗体:
分子量

313.35

Formula

C20H15N3O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DHODH-IN-31 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DHODH-IN-31Dihydroorotate DehydrogenaseSARS-CoVDHODHSARS coronavirusdihydroorotate dehydrogenaseantiviralSARS-CoV-2infectionVeroSH-SY5YCalu-3Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-178156
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