1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. DPC-AJ1951 TFA

DPC-AJ1951 TFA,一种含 14 个氨基酸的肽,可作为甲状旁腺激素 (PTH)/PTH 相关肽受体 (PPR) 的有效激动剂,并在离体和体内骨吸收试验中发挥作用。

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Custom Peptide Synthesis

DPC-AJ1951 TFA Chemical Structure

DPC-AJ1951 TFA Chemical Structure

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1 mg ¥1600
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5 mg ¥4000
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10 mg ¥6000
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption[1].

体外研究
(In Vitro)

DPC-AJ1951 TFA induces intracellular Ca2+ mobilization in HEK 293 cells transfected with the human PPR (EC50 26±14 nM)[1][1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1666.99 (free base)

Formula

C76H127N23O19.xC2HF3O2

性状

固体

颜色

White to off-white

Sequence

{Aib}-Val-{Aib}-Glu-Ile-Gln-Leu-{Nle}-His-Gln-Arg-Ala-Lys-Tyr-NH2

Sequence Shortening

{Aib}V{Aib}EIQL{Nle}HQRAKY-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 100 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DPC-AJ1951 TFA
目录号:
HY-P1418A
需求量: