1. Metabolic Enzyme/Protease
  2. Dipeptidyl Peptidase
  3. Dutogliptin tartrate

Dutogliptin tartrate  (Synonyms: PHX-1149)

目录号: HY-10286A
产品使用指南

Dutogliptin tartrate (PHX-1149) 是一种口服有效的选择性二肽基肽酶-4 (DPP4) 抑制剂,可用于 2 型糖尿病的研究。

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Dutogliptin tartrate Chemical Structure

Dutogliptin tartrate Chemical Structure

CAS No. : 890402-81-0

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Dutogliptin tartrate 的其他形式现货产品:

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查看 Dipeptidyl Peptidase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.

IC50 & Target

DPP4[1]

体内研究
(In Vivo)

Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a Tmax of 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

391.18

Formula

C14H26BN3O9

CAS 号
中文名称

杜拓格利普汀酒石酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Dutogliptin tartrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dutogliptin tartrate
目录号:
HY-10286A
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