1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Pomalidomide-C2-NH2 hydrochloride

Pomalidomide-C2-NH2 hydrochloride (Synonyms: Cereblon Ligand-Linker Conjugates 15 hydrochloride)

目录号: HY-128846A 纯度: 96.05%
产品使用指南

Pomalidomide-C2-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker。

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Pomalidomide-C2-NH2 hydrochloride Chemical Structure

Pomalidomide-C2-NH2 hydrochloride Chemical Structure

CAS No. : 2305369-00-8

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥3850 In-stock
5 mg ¥3500 In-stock
10 mg ¥5500 In-stock
50 mg ¥16500 In-stock
100 mg ¥22500 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

IC50 & Target

Cereblon

 

Molecular Weight

352.77

Formula

C₁₅H₁₇ClN₄O₄

CAS No.

2305369-00-8

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCN)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (354.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8347 mL 14.1735 mL 28.3471 mL
5 mM 0.5669 mL 2.8347 mL 5.6694 mL
10 mM 0.2835 mL 1.4174 mL 2.8347 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。 -80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Pomalidomide-C2-NH2Cereblon Ligand-Linker Conjugates 15E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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产品名称:
Pomalidomide-C2-NH2 hydrochloride
目录号:
HY-128846A
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