1. PROTAC
  2. Ligand for E3 Ligase
  3. E3 ligase Ligand 17 hydrochloride

E3 ligase Ligand 17 hydrochloride 

目录号: HY-128846A
产品使用指南

E3 ligase Ligand 17 hydrochloride 是一种 E3 泛素连接酶配体。E3 ligase Ligand 17 hydrochloride 可以通过 linker 与靶蛋白配体连接,形成 PROTAC 或 SNIPER。PROTAC 可诱导促癌蛋白发生泛素化降解。

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E3 ligase Ligand 17 hydrochloride Chemical Structure

E3 ligase Ligand 17 hydrochloride Chemical Structure

CAS No. : 2305369-00-8

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Description

E3 ligase Ligand 17 hydrochloride is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Molecular Weight

352.77

Formula

C₁₅H₁₇ClN₄O₄

CAS No.

2305369-00-8

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCN)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (354.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8347 mL 14.1735 mL 28.3471 mL
5 mM 0.5669 mL 2.8347 mL 5.6694 mL
10 mM 0.2835 mL 1.4174 mL 2.8347 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
References
  • 摩尔计算器

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This equation is commonly abbreviated as: C1V1 = C2V2

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产品名称:
E3 ligase Ligand 17 hydrochloride
目录号:
HY-128846A
需求量:

E3 ligase Ligand 17 hydrochloride

Cat. No.: HY-128846A