1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. E3 Ligase Ligand-Linker Conjugates 54

E3 Ligase Ligand-Linker Conjugates 54 

目录号: HY-125884
产品使用指南

Ligand-Linker Conjugates 54 包含用于 E3 泛素连接酶 cereblon (CRBN) 配体 pomalidomide 和 linker,用于 PROTAC 技术中。

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E3 Ligase Ligand-Linker Conjugates 54 Chemical Structure

E3 Ligase Ligand-Linker Conjugates 54 Chemical Structure

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Description

E3 Ligase Ligand-Linker Conjugates 54 incorporates a cereblon (CRBN) ligand pomalidomide for the E3 ubiquitin ligase, and a PROTAC linker, used in PROTAC technology[1].

IC50 & Target

Cereblon

 

Molecular Weight

599.68

Formula

C₃₀H₄₁N₅O₈

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NC(CCCCC(NCCCCCCNC(OC(C)(C)C)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
E3 Ligase Ligand-Linker Conjugates 54
目录号:
HY-125884
需求量:

E3 Ligase Ligand-Linker Conjugates 54

Cat. No.: HY-125884