2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. Eflapegrastim

Eflapegrastim 是一种人源 IgG4 单抗 ，也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向 G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化，维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Eflapegrastim Chemical Structure

Eflapegrastim Chemical Structure

CAS No. : 1384099-30-2

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
1 mg   询价  
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Eflapegrastim 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eflapegrastim is a human IgG4 monoclonal antibody, is also a granulocyte colony-stimulating factor (G-CSF). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia[1].

体外研究
(In Vitro)

Eflapegrastim has an IgG4 Fc fragment and short polyethylene glycol linker[1].
Eflapegrastim (5.5-88 mM; 4 min) binds to FcRn but not Fcγ receptors or C1q[1].
Eflapegrastim (0.000036-0.709 nmol/L; 54 h) induces bone marrow cell proliferation[1].
Eflapegrastim (10 μM; 1 h) binds FcRn and undergoes FcRn-mediated transcytosis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Eflapegrastim 相关抗体:
体内研究
(In Vivo)

Eflapegrastim (100 μg/kg; s.c.; single dose) decreases the duration of neutropenia (DN) and increases levels of G-CSF in serum and marrow in chemotherapy-induced neutropenic rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6NCrl mice (4-6 weeks old)[1]
Dosage: (1) 9, 26, 53, and 88 µg/kg; (2) 62 µg/kg
Administration: Subcutaneous injection; single dose
Result: Reduced chemotherapy-induced neutropenia.
Clinical Trial
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Eflapegrastim 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eflapegrastim1384099-30-2c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1RInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Eflapegrastim
目录号：
HY-P99913
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z