2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Efmirenpase alfa

Efmirenpase alfa 是一种 Fc-ENPP1 融合蛋白 (人源 IgG1 Fc 结构域连接至修饰的人源 ENPP1)。与天然人源 ENPP1 相比，Efmirenpase alfa 具有更长的半衰期和更高的受体亲和力。Efmirenpase alfa 可作为一种酶替代疗法用于 ENPP1 缺乏症 (如动脉钙化和低磷血症性佝偻病) 研究。

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Efmirenpase alfa

Efmirenpase alfa Chemical Structure

CAS No. : 2770242-54-9

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Efmirenpase alfa 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research[1][2].

同型

human E-NPP1 fused via peptide linker to a human immunoglobulin G1 (IgG1) Fc fragment
反应种属

Human
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Efmirenpase alfa 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Efmirenpase alfa2770242-54-9Phosphodiesterase (PDE)Fusion proteinFc-ENPP1Enzyme replacement therapyArterial calcificationHypophosphatemic ricketsInhibitorinhibitorinhibit

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