2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. Efzimfotase alfa

Efzimfotase alfa  (Synonyms: ALXN-1850)

目录号: HY-P991210
技术支持

Efzimfotase alfa (ALXN-1850) 是靶向组织非特异性碱性磷酸酶 (TNSALP) 缺乏的酶替代治疗剂。Efzimfotase alfa 通过水解 TNSALP 底物，降低无机焦磷酸盐 (PPi) 和吡哆醛 5 ' -磷酸 (PLP) 等底物的浓度发挥作用。Efzimfotase alfa 有望用于低磷血症 (HPP) 的研究。

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Efzimfotase alfa

Efzimfotase alfa Chemical Structure

CAS No. : 2746354-58-3

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Efzimfotase alfa 相关抗体

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生物活性

Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP)[1][2].

同型

Fusion-[Homo sapiens ALPL (alkaline phosphatase, TNSALP, tissue non-specific alkaline phosphatase) 18-502]2-IGHG4 Fc (Fragment constant)-deca-aspartate
Clinical Trial
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Efzimfotase alfa 相关分类

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Keywords:

Efzimfotase alfa2746354-58-3ALXN-1850ALXN1850ALXN 1850PhosphataseTNSALPPpiPLPHPPInhibitorinhibitorinhibit

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