Ethyl phenylglyoxylate-d₅  (Synonyms: Ethyl benzoylformate-d₅; Phenylglyoxylic acid ethyl ester-d₅)

Ethyl phenylglyoxylate-d₅ (Ethyl benzoylformate-d₅; Phenylglyoxylic acid ethyl ester-d₅) is the deuterium labeled Ethyl phenylglyoxylate (HY-W016618). Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions^[1][2][3].

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

183.22

C₁₀H₅D₅O₃

1025892-26-5

1603-79-8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Shengkui Hu, et al. Photochemically Active Polymers Containing Pendant Ethyl Phenylglyoxylate. Macromolecules 1998, 31, 2, 322-327.

  [2]. Hu S, et al. Photoreduction of ethyl phenylglyoxylate. Journal of Photochemistry and Photobiology A: Chemistry, 1998, 114(2): 103-108.

  [3]. Berndt M C, et al. Ethyl phenylglyoxylate, a simultaneous inhibitor and substrate of chicken liver carboxylesterase (EC 3.1. 1.1). Enzyme-catalyzed fragmentation of (E)-benzil monoxime O-2, 4-dinitrophenyl ether. Journal of the American Chemical Society, 1977, 99(25): 8334-8335.