1. Anti-infection
  2. Bacterial
  3. G907

G907 

目录号: HY-125176
产品使用指南

G907 是一种具有杀菌活性的选择性小分子拮抗剂,抑制 ABC transporter,MsbA (IC50=18 nM)。 G907 通过楔入结构上保守的跨膜袋,使 MsbA 陷入向内的脂多糖结合构象中。

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G907 Chemical Structure

G907 Chemical Structure

CAS No. : 2244035-16-1

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Description

G907, a selective small molecule ATP-binding cassette (ABC) transporter, MsbA antagonist with bactericidal activity (IC50=18 nM). G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket[1].

IC50 & Target

IC50: 18 nM (ABC transporter)[1]

Molecular Weight

433.93

Formula

C₂₆H₂₄ClNO₃

CAS No.

2244035-16-1

SMILES

O=C(O)/C=C/C1=C(C2CC2)C3=CC(OC(C4=C(C5CC5)C=CC=C4Cl)C)=CC=C3N=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
G907
目录号:
HY-125176
需求量:

G907

Cat. No.: HY-125176