2. Apoptosis
  3. Apoptosis
  4. Ganoderic acid R

Ganoderic acid R 是一种有效的抗癌剂。Ganoderic acid R 通过诱导肿瘤细胞系凋亡 (apoptosis) 来抑制生长。 Ganoderic acid R 对多药耐药 (MDR) 肿瘤细胞系 (KB-A-1/Dox) 和敏感肿瘤细胞系 (KB-A-1) 具有显著的细胞毒性。

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Ganoderic acid R Chemical Structure

Ganoderic acid R Chemical Structure

CAS No. : 103963-39-9

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Ganoderic acid R 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1)[1].

体外研究
(In Vitro)

Ganoderic acid R (0-50 µg/mL, 48 h) 在浓度超过 20 µg/mL时通过诱导肿瘤细胞系凋亡来抑制生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ganoderic acid R 相关抗体:

Apoptosis Analysis[1]

Cell Line: KB-A-1/Dox cells
Concentration: 0, 25, 50 μg/mL
Incubation Time: 48 h
Result: Induced the cellular apoptosis, the number of apoptotic cells was increased from 35% to 90% during 48 h.
分子量

554.76

Formula

C34H50O6
CAS 号
结构分类
初始来源

glossy ganoderma
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ganoderic acid R 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderic acid R103963-39-9ApoptosisAnticancerKB-A-1/Dox cellsKB-A-1 cellsGanoderic acidInhibitorinhibitorinhibit

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