1. Apoptosis
  2. Apoptosis
  3. Ganoderic acid S

Ganoderic acid S 是一种灵芝酸的位置异构体,可从 Ganoderma lucidum 的发酵菌丝体中分离得到。 Ganoderic acid S 可通过线粒体途径诱导 HeLa 细胞发生细胞凋亡 (apoptosis)。

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Ganoderic acid S Chemical Structure

Ganoderic acid S Chemical Structure

CAS No. : 103963-38-8

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生物活性

Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway[1].

体外研究
(In Vitro)

Ganoderic acid S (0, 39.1, 97.7 μM; 12 h) 在 HeLa 细胞中导致细胞周期停滞在 S 期[1]
Ganoderic acid S 剂量依赖性地导致线粒体膜电位的崩溃。Ganoderic acid S 诱导细胞色素 c 从线粒体大量释放到 HeLa 细胞的胞质溶胶中[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis[1]

Cell Line: HeLa cells
Concentration: 0, 39.1, 97.7 μM
Incubation Time: 12 h
Result: Caused cell cycle arrest in the S phase.
分子量

512.72

Formula

C32H48O5

CAS 号
结构分类
初始来源

Ganoderma lucidum

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Ganoderic acid S 相关分类

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