1. Gene
  2. Faah - fatty acid amide hydrolase Gene

Faah - fatty acid amide hydrolase Gene

中文名称:脂肪酸酰胺水解酶

种属: Rattus norvegicus

基因 ID: 100911581 | 基因类型: protein coding

关于 Faah

Primary_assembly 5: 129,479,824-129,498,677 reverse strand.mRatBN7.2:CM026978.1

This gene has 2 transcripts (splice variants), 131 orthologues, 1 paralogue and is associated with 6 phenotypes. Biased expression in Liver (RPKM 24.3), Brain (RPKM 57.9) and 6 other tissues.

功能概要

该基因编码的蛋白可启动多种功能,包括酰基甘油脂肪酶活性;水解酶活性,作用于线性酰胺中的碳氮(但不是肽)键;和相同的蛋白质结合活性。参与脂肪酸分解代谢过程;单酰基甘油分解代谢过程;和血管收缩的正调节作用。位于细胞器膜上。该基因的人类直系同源物与肥胖和物质相关疾病有关。与人 FAAH(脂肪酸酰胺水解酶)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables several functions, including acylglycerol Lipase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; and identical protein binding activity. Involved in fatty acid catabolic process; monoacylglycerol catabolic process; and positive regulation of vasoconstriction. Located in organelle membrane. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Orthologous to human FAAH (fatty acid amide hydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Faah 基因产物(1)

mRNA Protein Name
NM_001369126.1 NP_001356055.1 fatty-acid amide hydrolase 1

Faah 蛋白结构

Amidase

Amidase: cl18951 (94 - 561)

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  • 579 a.a.
蛋白主名 其他名称

fatty-acid amide hydrolase 1

anandamide amidase

anandamide amidohydrolase 1

fatty acid ester hydrolase

oleamide hydrolase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Faah NCBI NCBI:2166