2. Gene
  3. Slc6a5 - solute carrier family 6 (neurotransmitter transporter, glycine), member 5 Gene

Slc6a5 - solute carrier family 6 (neurotransmitter transporter, glycine), member 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 6 (神经递质转运蛋白，甘氨酸) ，成员 5

种属: Mus musculus

同用名: Glyt2; prestin

基因 ID: 104245 | 基因类型: protein coding

关于 Slc6a5

Chromosome 7: 49,559,894-49,613,604 forward strand.GRCm39:CM001000.3

This gene has 4 transcripts (splice variants), 210 orthologues, 20 paralogues and is associated with 34 phenotypes. Biased expression in cerebellum adult (RPKM 13.1), CNS E14 (RPKM 1.8) and 2 other tissues.

功能概要

预计该基因编码的蛋白可启动甘氨酸：钠同向转运体活性。参与神经递质再摄取。在甘氨酸能突触中活跃。以多种结构表达，包括肾上腺；中枢神经系统;食管;镜片;和雄性生殖腺或器官。用于研究惊跳过度 3。该基因的人类直向同源物与惊跳过度 3 相关。与人类 SLC6A5（溶质载体家族 6 成员 5）直向同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable glycine:sodium symporter activity. Involved in neurotransmitter reuptake. Is active in glycinergic synapse. Is expressed in several structures, including adrenal gland; central nervous system; esophagus; lens; and male reproductive gland or organ. Used to study hyperekplexia 3. Human ortholog(s) of this gene implicated in hyperekplexia 3. Orthologous to human SLC6A5 (solute carrier family 6 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a5 基因产物(2)

mRNA Protein Name
NM_001146013.1 NP_001139485.1 sodium- and chloride-dependent glycine transporter 2 isoform a
NM_148931.3 NP_683733.2 sodium- and chloride-dependent glycine transporter 2 isoform b

Slc6a5 蛋白结构

SLC6sbd_GlyT2

SLC6sbd_GlyT2: cd11499 (192 - 788)

  • 0
  • 200
  • 400
  • 600
  • 799 a.a.
蛋白主名 其他名称

sodium- and chloride-dependent glycine transporter 2

glyT-2

glycine transporter 2

solute carrier family 6 member 5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13314 SLC6A5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13315 Slc6a5 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13316 Slc6a5 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc6a5 NCBI NCBI:9152
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