2. Gene
  3. Jmjd6 - jumonji domain containing 6 Gene

Jmjd6 - jumonji domain containing 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PSR; Ptdsr; PtdSerR; mKIAA0585; D11Ertd195e; 5730436I23Rik

基因 ID: 107817 | 基因类型: protein coding

关于 Jmjd6

功能概要

This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein functions in differentiation of multiple tissues during development, and in anti-inflammatory cytokine signaling. It was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that this protein does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. [provided by RefSeq, Jul 2008]

Jmjd6 基因产物(2)

mRNA Protein Name
NM_001363363.1 NP_001350292.1 bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform 1
NM_033398.3 NP_203971.2 bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
21060799 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
21060799 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21300889 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
10811223 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell differentiation in thymus IMP
IMP: 通过突变表型推断
14715629 MGI
NOT acts upstream of or within apoptotic cell clearance IMP
IMP: 通过突变表型推断
15345036 MGI
acts upstream of or within apoptotic cell clearance IMP
IMP: 通过突变表型推断
14715629 MGI
acts upstream of or within blood vessel development IMP
IMP: 通过突变表型推断
15615595 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
10811223 MGI
acts upstream of or within erythrocyte development IMP
IMP: 通过突变表型推断
14715629 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
15615595 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
15345036 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
14645847 MGI
acts upstream of or within macrophage activation IMP
IMP: 通过突变表型推断
15345036 MGI
involved in negative regulation of protein homooligomerization IDA
IDA: 通过直接分析推断
33443146 MGI
involved in non-membrane-bounded organelle assembly IDA
IDA: 通过直接分析推断
33443146 MGI
acts upstream of or within recognition of apoptotic cell IDA
IDA: 通过直接分析推断
10811223 MGI
acts upstream of or within recognition of apoptotic cell IMP
IMP: 通过突变表型推断
14645847 MGI
involved in regulation of mRNA splicing, via spliceosome IMP
IMP: 通过突变表型推断
21300889 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
15345036 MGI
involved in sprouting angiogenesis IMP
IMP: 通过突变表型推断
21300889 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
21060799 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
21060799 MGI
located in nucleoplasm IDA
IDA: 通过直接分析推断
21060799 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
33443146 MGI
located in nucleus IDA
IDA: 通过直接分析推断
14729065 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10811223 MGI
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
21060799 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

apoptotic cell clearance receptor PtdSerR

histone arginine demethylase JMJD6

jmjC domain-containing protein 6

jumonji domain-containing protein 6

lysyl-hydroxylase JMJD6

peptide-lysine 5-dioxygenase JMJD6

phosphatidylserine receptor

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139782 SKLB325 99.23% 否
HY-139434 JMJD6-IN-1 Inhibitor 99.69% 否
HY-P10445 TAT-PiET Inhibitor / 否
HY-P10446 TAT-PiET-PROTAC Inhibitor / 否
HY-RS07039 JMJD6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17009 Jmjd6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23452 Jmjd6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jmjd6 NCBI NCBI:23210
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