2. Gene
  3. FGL2 - fibrinogen like 2 Gene

FGL2 - fibrinogen like 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：纤维蛋白原样 2

种属: Homo sapiens

同用名: T49; pT49

基因 ID: 10875 | 基因类型: protein coding

关于 FGL2

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:77,193,369-77,199,819 (from NCBI)

This gene has 2 transcripts (splice variants), 278 orthologues and 25 paralogues. Broad expression in spleen (RPKM 83.3), appendix (RPKM 61.0) and 22 other tissues.

功能概要

该基因编码的蛋白质是一种分泌型蛋白质，类似于纤维蛋白原的 β 链和 γ 链。编码蛋白的羧基末端由纤维蛋白原相关结构域 (FRED) 组成。编码的蛋白质形成四聚体复合物，通过链间二硫键稳定。这种蛋白质可能在粘膜部位的生理功能中发挥作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008]

FGL2 基因产物(1)

mRNA Protein Name
NM_006682.3 NP_006673.1 fibroleukin precursor

FGL2 蛋白结构

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (210 - 435)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 439 a.a.
蛋白主名 其他名称

fibroleukin

fibrinogen-like protein 2

重组 FGL2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78992 FGL2 Protein, Human (CHO, His) Q14314 (N24-P439 ) ≥95%
HY-P700721 FGL2 Protein, Human (HEK293, His-Avi, Flag) Q14314 (V205-P439) ≥95%
HY-P700987 FGL2 Protein, Human (Biotinylated, HEK293, His-Avi, Flag) Q14314 (V205-P439) ≥95%
HY-P701078 FGL2 Protein, Human (HEK293, hFc-Flag) Q14314 (V205-P439) ≥95%

关联疾病

疾病名称 别名
Viral Hepatitis

Animal Viral Hepatitis

Hepatitis, Viral, Animal

Human Viral Hepatitis

Viral Hepatitis With Hepatic Coma
Hepatitis B

Chronic Hepatitis B

Hepatitis B Infection

Serum Hepatitis

HBV

Hepatitis B Chronic

Hbv, Susceptibility To

Hepatitis B, Chronic

Chronic Hepatitis B Without Delta Agent

Chronic Hbv - [Hepatitis B Virus] Infection

Hepatitis B Nos

Chronic Type B Viral Hepatitis

Hep B Nos
Ileum Cancer

Ileal Neoplasm

Malignant Neoplasm Of Ileum

Ileal Cancer

Ileal Neoplasms
Autoimmune Glomerulonephritis
Pontocerebellar Hypoplasia, Type 3

Pontocerebellar Hypoplasia Type 3

Cerebellar Atrophy With Progressive Microcephaly

PCH3

Clam

Pch With Optic Atrophy

Pontocerebellar Hypoplasia 3

Hypoplasia, Pontocerebellar, Type 3
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04928 FGL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus FGL2 VGNC VGNC:80044
Rattus norvegicus FGL2 RGD RGD:620170
Mus musculus FGL2 MGD MGI:103266
Macaca mulatta FGL2 VGNC VGNC:72657
Bos taurus FGL2 VGNC VGNC:28993
Canis familiaris FGL2 VGNC VGNC:40865
Macaca fascicularis FGL2 NCBI
Others FGL2 NCBI
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