2. Gene
  3. Hadh - hydroxyacyl-CoA dehydrogenase Gene

Hadh - hydroxyacyl-CoA dehydrogenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Hadhsc

基因 ID: 113965 | 基因类型: protein coding

关于 Hadh

功能概要

Enables 3-hydroxyacyl-CoA dehydrogenase activity. Involved in several processes, including fatty acid beta-oxidation; negative regulation of Insulin secretion; and response to activity. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in mitochondrion. Biomarker of myocardial infarction and obesity. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Hadh 基因产物(1)

mRNA Protein Name
NM_057186.2 NP_476534.1 hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-hydroxyacyl-CoA dehydrogenase activity IMP
IMP: 通过突变表型推断
17491019 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fatty acid beta-oxidation IMP
IMP: 通过突变表型推断
17491019 RGD
involved in negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
17491019 RGD
involved in response to activity IDA
IDA: 通过直接分析推断
8231758 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
18191600 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
7050060 RGD
involved in response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
12176671 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

HCDH

L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain

hydroxylacyl-Coenzyme A dehydrogenase, short chain

medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase

short-chain 3-hydroxyacyl-CoA dehydrogenase

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-178918 XZA-1 / 否
HY-E70239 2-Methylbutyryl-CoA / 否
HY-RS05989 HADH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05990 HADHA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17745 Hadh Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24211 Hadh Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hadh NCBI NCBI:3033
Mus musculus Hadh NCBI NCBI:15107
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