2. Gene
  3. Ncoa6 - nuclear receptor coactivator 6 Gene

Ncoa6 - nuclear receptor coactivator 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: NRC; Aib3; PRIP; Trbp; RAP250

基因 ID: 116464 | 基因类型: protein coding

关于 Ncoa6

功能概要

Enables several functions, including nuclear receptor binding activity; nuclear receptor coactivator activity; and peroxisome proliferator activated receptor binding activity. Involved in ovarian follicle development; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-containing complex. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in breast cancer; colon cancer; and lung Cancer. Orthologous to human NCOA6 (nuclear receptor coactivator 6). [provided by Alliance of Genome Resources, Apr 2022]

Ncoa6 基因产物(1)

mRNA Protein Name
NM_001276714.1 NP_001263643.1 nuclear receptor coactivator 6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables nuclear estrogen receptor binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables nuclear glucocorticoid receptor binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables nuclear receptor coactivator activity IDA
IDA: 通过直接分析推断
10866662 RGD
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables nuclear thyroid hormone receptor binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables nuclear vitamin D receptor binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables peroxisome proliferator activated receptor binding IPI
IPI: 通过物理相互作用推断
12189208 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10866662 RGD
enables protein domain specific binding IMP
IMP: 通过突变表型推断
17536006 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ovarian follicle development IEP
IEP: 通过表达模式推断
12374465 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
16738321 RGD
involved in positive regulation of peptide secretion IMP
IMP: 通过突变表型推断
16738321 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10866662 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of protein-containing complex IDA
IDA: 通过直接分析推断
10866662 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor coactivator 6

PPAR-interacting protein

activating signal cointegrator 2

amplified in breast cancer protein 3

cancer-amplified transcriptional coactivator ASC-2

nuclear receptor-activating protein, 250 kDa

peroxisome proliferator-activated receptor-interacting prot

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09094 NCOA6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20060 Ncoa6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26564 Ncoa6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncoa6 NCBI NCBI:23054
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