2. Gene
  3. Araf - Araf proto-oncogene, serine/threonine kinase Gene

Araf - Araf proto-oncogene, serine/threonine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: A-Raf; Araf1; 1200013E08Rik

基因 ID: 11836 | 基因类型: protein coding

关于 Araf

功能概要

Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in several processes, including MAPK cascade; regulation of TOR signaling; and regulation of cellular protein metabolic process. Predicted to act upstream of or within phosphorylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and retina. Orthologous to human ARAF (A-Raf proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Araf 基因产物(2)

mRNA Protein Name
NM_001159645.1 NP_001153117.1 serine/threonine-protein kinase A-Raf isoform 2
NM_009703.2 NP_033833.1 serine/threonine-protein kinase A-Raf isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9488663 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
12931191 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase A-Raf

A-Raf proto-oncogene serine/threonine-protein kinase

proto-oncogene A-Raf

raf-related oncogene

v-raf murine sarcoma 3611 viral oncogene homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158115 NST-628 Inhibitor 98.61% 否
HY-162752 Anticancer agent 250 / 否
HY-169869 pan-Raf/RTK inhibitor 1 Inhibitor / 否
HY-178042 SS-3091 Inhibitor / 否
HY-18652A Avutometinib potassium Inhibitor / 否
HY-E70103I exo-α-1,3-Arabinofuranosidase, Penicillium chrysogenum / 否
HY-RS00886 ARAF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18462 Araf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24943 Araf Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Araf NCBI NCBI:369
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