2. Gene
  3. Arf6 - ADP-ribosylation factor 6 Gene

Arf6 - ADP-ribosylation factor 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 11845 | 基因类型: protein coding

关于 Arf6

功能概要

Enables protein N-terminus binding activity. Involved in several processes, including negative regulation of protein localization to cell surface; positive regulation of focal adhesion disassembly; and positive regulation of keratinocyte migration. Acts upstream of or within several processes, including hepatocyte apoptotic process; liver development; and myeloid cell apoptotic process. Located in endosome and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system; and respiratory system. Orthologous to human ARF6 (ADP ribosylation factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Arf6 基因产物(1)

mRNA Protein Name
NM_007481.3 NP_031507.1 ADP-ribosylation factor 6
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20493856 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within erythrocyte apoptotic process IMP
IMP: 通过突变表型推断
16880525 MGI
acts upstream of or within establishment of epithelial cell polarity IMP
IMP: 通过突变表型推断
20080746 MGI
acts upstream of or within hepatocyte apoptotic process IMP
IMP: 通过突变表型推断
16880525 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
16880525 MGI
involved in negative regulation of protein localization to cell surface IDA
IDA: 通过直接分析推断
29420262 MGI
involved in positive regulation of focal adhesion disassembly IMP
IMP: 通过突变表型推断
25490267 MGI
involved in positive regulation of keratinocyte migration IMP
IMP: 通过突变表型推断
25490267 MGI
involved in positive regulation of protein localization to plasma membrane IDA
IDA: 通过直接分析推断
16751103 MGI
involved in protein localization to cell surface IDA
IDA: 通过直接分析推断
16751103 MGI
involved in protein localization to endosome IMP
IMP: 通过突变表型推断
23572513 MGI
involved in regulation of dendritic spine development IMP
IMP: 通过突变表型推断
16325184 MGI
acts upstream of or within regulation of neuron projection development IMP
IMP: 通过突变表型推断
27330119 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
8947846 MGI
located in endosome IDA
IDA: 通过直接分析推断
16751103 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
8947846 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ADP-ribosylation factor 6

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112473 NAV-2729 Inhibitor 99.10% 否
HY-139950 Rasarfin Inhibitor 99.57% 否
HY-P10178 Myristoylated ARF6 (2-13) Inhibitor / 否
HY-P10179 ARF6 (2-13) / 否
HY-RS00898 ARF6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18229 Arf6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24708 Arf6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arf6 NCBI NCBI:382
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