2. Gene
  3. Klf5 - Kruppel-like factor 5 Gene

Klf5 - Kruppel-like factor 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CKLF; IKLF; Bteb2; 4930520J07Rik

基因 ID: 12224 | 基因类型: protein coding

关于 Klf5

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; MRF binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of transcription, DNA-templated; and skeletal muscle tissue regeneration. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human KLF5 (Kruppel like factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Klf5 基因产物(1)

mRNA Protein Name
NM_009769.4 NP_033899.2 Krueppel-like factor 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12101409 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
12101409 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
27743478 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IGI
IGI: 通过遗传相互作用推断
27743478 MGI
enables MRF binding IPI
IPI: 通过物理相互作用推断
27743478 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
27743478 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IGI
IGI: 通过遗传相互作用推断
27743478 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12101409 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
12101409 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within intestinal epithelial cell development IMP
IMP: 通过突变表型推断
23266329 MGI
acts upstream of microvillus assembly IMP
IMP: 通过突变表型推断
12101409 MGI
acts upstream of or within myotube differentiation involved in skeletal muscle regeneration IDA
IDA: 通过直接分析推断
27743478 MGI
acts upstream of or within myotube differentiation involved in skeletal muscle regeneration IMP
IMP: 通过突变表型推断
27743478 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
23266329 MGI
acts upstream of or within positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
12101409 MGI
acts upstream of or within positive regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
20719859 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
27743478 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
27743478 MGI
acts upstream of or within positive regulation of transcription by transcription factor localization IDA
IDA: 通过直接分析推断
27743478 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
27743478 MGI
acts upstream of regulation of microvillus assembly IMP
IMP: 通过突变表型推断
23266329 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23266329 MGI
acts upstream of or within satellite cell activation involved in skeletal muscle regeneration IMP
IMP: 通过突变表型推断
27743478 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
22147266 MGI
acts upstream of or within skeletal muscle satellite cell differentiation IMP
IMP: 通过突变表型推断
27743478 MGI
acts upstream of or within skeletal muscle tissue regeneration IMP
IMP: 通过突变表型推断
27743478 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
21503901 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
27743478 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Krueppel-like factor 5

BTE-binding protein 2

basic transcription element-binding protein 2

intestinal-enriched krueppel-like factor

transcription factor BTEB2

Klf5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Klf5 Q9Z0Z7 FBXW7 Homo sapiens Q969H0
Anti Tag CoIP
22307056
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19994 ML264 Inhibitor 98.32% 否
HY-136530 SR18662 Inhibitor 99.61% 否
HY-N1570 Pterosin B Inhibitor 99.98% 否
HY-W011044 CID 5951923 Inhibitor 99.00% 否
HY-139691 SR15006 Inhibitor 99.95% 否
HY-RS07342 KLF5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-162875 PROTAC BRD4 Degrader-27 / 否
HY-169213 LN-439A Inhibitor / 否
HY-RS16676 Klf5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23111 Klf5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Klf5 NCBI NCBI:688
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