2. Gene
  3. Cbx4 - chromobox 4 Gene

Cbx4 - chromobox 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PC2; MPc2

基因 ID: 12418 | 基因类型: protein coding

关于 Cbx4

功能概要

Enables several functions, including SUMO binding activity; SUMO transferase activity; and nucleic acid binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and protein sumoylation. Located in nuclear body. Is expressed in several structures, including adrenal gland; brain; gut; lung; and thymus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human CBX4 (chromobox 4). [provided by Alliance of Genome Resources, Apr 2022]

Cbx4 基因产物(1)

mRNA Protein Name
NM_007625.2 NP_031651.2 E3 SUMO-protein ligase CBX4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SUMO binding IDA
IDA: 通过直接分析推断
20176810 MGI
enables SUMO transferase activity EXP
EXP: 通过实验结果推断
17439403 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
17392792 MGI
enables methylated histone binding IDA
IDA: 通过直接分析推断
16537902 MGI
enables phosphoprotein binding IPI
IPI: 通过物理相互作用推断
9367786 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9367786 MGI
enables single-stranded RNA binding IDA
IDA: 通过直接分析推断
16537902 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
20417598 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9367786 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
20417598 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17392792 MGI
acts upstream of or within protein sumoylation IMP
IMP: 通过突变表型推断
20176810 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear body IDA
IDA: 通过直接分析推断
20417598 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16537902 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 SUMO-protein ligase CBX4

E3 SUMO-protein transferase CBX4

chromobox homolog 4

chromobox protein homolog 4

polycomb 2 homolog

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-178918 XZA-1 / 否
HY-RS02011 CBX4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20702 Cbx4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27213 Cbx4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cbx4 NCBI NCBI:8535
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