1. Gene
  2. Emd - emerin Gene

Emd - emerin Gene

种属: Mus musculus

同用名: Sta

基因 ID: 13726 | 基因类型: protein coding

关于 Emd

功能概要

This gene is the founding member of the LEM (Lap2beta, Emerin, and Man1) domain gene family. It encodes an integral membrane protein of the inner nuclear membrane. This gene may be involved in transcriptional regulation and genomic organization. In humans, mutations in this gene cause a class of diseases called laminopathies, which includes Emery-Dreifuss muscular dystrophy (EDMD). [provided by RefSeq, Apr 2013]

Emd 基因产物(11)

mRNA Protein Name
NM_001410134.1 NP_001397063.1 emerin isoform 2
NM_001410135.1 NP_001397064.1 emerin isoform 2
NM_001410136.1 NP_001397065.1 emerin isoform 3
NM_001410137.1 NP_001397066.1 emerin isoform 4
NM_001410138.1 NP_001397067.1 emerin isoform 4
NM_001410139.1 NP_001397068.1 emerin isoform 4
NM_001410140.1 NP_001397069.1 emerin isoform 5
NM_001410141.1 NP_001397070.1 emerin isoform 6
NM_001410142.1 NP_001397071.1 emerin isoform 7
NM_001410143.1 NP_001397072.1 emerin isoform 8
NM_007927.4 NP_031953.1 emerin isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19933576 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within skeletal muscle cell differentiation IGI
IGI: 通过遗传相互作用推断
19720741 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
19720741 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in TMEM240-body IDA
IDA: 通过直接分析推断
32535204 MGI
located in nuclear envelope IDA
IDA: 通过直接分析推断
19933576 MGI
located in nuclear membrane IDA
IDA: 通过直接分析推断
17164264 MGI
located in nucleus IDA
IDA: 通过直接分析推断
22349700 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

emerin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Emd NCBI NCBI:2010
Macaca fascicularis Emd NCBI NCBI:102138141