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Eniporide  (Synonyms: EMD-96785)

目录号: HY-106150
产品使用指南

Eniporide (EMD 96785) 是一种 Na(+)/H(+) 交换 (NHE) 抑制剂。Eniporide 特异性抑制 NHE-1 同工型。Eniporide 可改善动物中与心肌缺血/再灌注相关的心脏性能抑制,限制梗塞面积。Eniporide 在体外循环 (CPB) 和心脏骤停的临床相关的猪模型中调节心脏性能和高能量磷酸盐含量。

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Eniporide Chemical Structure

Eniporide Chemical Structure

CAS No. : 176644-21-6

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Eniporide 的其他形式现货产品:

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eniporide (EMD 96785) is a Na(+)/H(+) exchange (NHE) inhibitor. Eniporide specifically inhibits the NHE-1 isoform. Eniporide improves cardiac performance inhibition associated with myocardial ischemia/reperfusion in animals, and limits infarct size in experimental models. Eniporide regulates cardiac performance and high-energy phosphate content in clinically relevant pig models of CPB and cardiac arrest[1][2].

体外研究
(In Vitro)

ENIPORIDE 是一种有效的 Na+/H+ 交换抑制剂。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Eniporide (3mg /kg;静脉注射;心脏骤停前全身输注) 可改善晶体性心脏骤停引起的缺血/再灌注健康猪心脏的功能和高能量磷酸盐含量[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Clinically relevant pig models of cardiopulmonary bypass (CPB) and cardioplegia[1]
Dosage: 3 mg/kg
Administration: IV; systemic infusion before cardioplegia with added 2 μM Eniporide or not
Result: Had no effect on standard hemodynamics including vascular pressures and cardiac index nor for cardiac performance factors.
Reduced myocardial edema and improves heart function.
分子量

320.37

Formula

C14H16N4O3S

CAS 号
中文名称

依泊来德

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Eniporide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Eniporide
目录号:
HY-106150
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