2. Gene
  3. SLC2A14 - solute carrier family 2 member 14 Gene

SLC2A14 - solute carrier family 2 member 14 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 2 成员 14

种属: Homo sapiens

同用名: GLUT14; SLC2A3P3

基因 ID: 144195 | 基因类型: protein coding

关于 SLC2A14

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,812,514-7,891,196 (from NCBI)

This gene has 21 transcripts (splice variants), 488 orthologues and 13 paralogues. Biased expression in testis (RPKM 31.0), bone marrow (RPKM 13.8) and 5 other tissues.

功能概要

葡萄糖转运蛋白 (GLUT) 家族的成员，包括 SLC2A14，是高度保守的整合膜蛋白，可将葡萄糖和果糖等己糖转运到所有哺乳动物细胞中。 GLUT 显示组织和细胞类型的特异性表达 (Wu 和 Freeze，2002 [PubMed 12504846]) 。[OMIM 提供，2008 年 3 月]

Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression (Wu and Freeze, 2002 [PubMed 12504846]).[supplied by OMIM, Mar 2008]

SLC2A14 基因产物(6)

mRNA Protein Name
NM_001286233.2 NP_001273162.1 solute carrier family 2, facilitated glucose transporter member 14 isoform a
NM_001286234.2 NP_001273163.1 solute carrier family 2, facilitated glucose transporter member 14 isoform b
NM_001286235.2 NP_001273164.1 solute carrier family 2, facilitated glucose transporter member 14 isoform b
NM_001286236.2 NP_001273165.1 solute carrier family 2, facilitated glucose transporter member 14 isoform c
NM_001286237.2 NP_001273166.1 solute carrier family 2, facilitated glucose transporter member 14 isoform d
NM_153449.4 NP_703150.1 solute carrier family 2, facilitated glucose transporter member 14 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables D-glucose transmembrane transporter activity IDA
IDA: 通过直接分析推断
28971850 GOA
enables dehydroascorbic acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
28971850 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in D-glucose transmembrane transport IDA
IDA: 通过直接分析推断
28971850 GOA
involved in dehydroascorbic acid transport IDA
IDA: 通过直接分析推断
28971850 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
27460888 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC2A14 蛋白结构

Sugar_tr

Sugar_tr: Sugar (and other) transporter (39 - 489)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 520 a.a.
蛋白主名 其他名称

solute carrier family 2, facilitated glucose transporter member 14

glucose transporter type 14

SLC2A14 抗体

目录号 产品名 应用 反应物种
HY-P83177 Glucose Transporter GLUT3 Antibody (YA2922) WB Human, Mouse, Rat
HY-P84682 SLC2A14 Antibody (YA4379) IHC-P, ICC/IF, ELISA Human

关联疾病

疾病名称 别名
Hypoascorbemia

Scurvy

Ascorbic Acid Deficiency

Vitamin C Deficiency

Vitamin C, Inability To Synthesize

Deficiency Of Vitamin C

Scorbutus

Vitamin C
Micronodular Basal Cell Carcinoma

Skin Micronodular Basal Cell Carcinoma

Basal Cell Carcinoma, Micronodular
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13163 SLC2A14 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SLC2A14 MGD MGI:95757
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