1. Gene
  2. Hcrt - hypocretin Gene

Hcrt - hypocretin Gene

种属: Mus musculus

同用名: PPOX

基因 ID: 15171 | 基因类型: protein coding

关于 Hcrt

功能概要

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors Hcrtr1 and Hcrtr2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Sep 2015]

Hcrt 基因产物(1)

mRNA Protein Name
NM_010410.2 NP_034540.1 hypocretin neuropeptide precursor precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
23700511 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11748295 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hypocretin neuropeptide precursor

hypocretin neuropeptide

orexin A

orexin B

prepro-orexin

preprohypocretin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcrt NCBI NCBI:3060