2. Gene
  3. CUX1 - cut like homeobox 1 Gene

CUX1 - cut like homeobox 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：切样同源盒 1

种属: Homo sapiens

同用名: CDP; CUX; p75; CASP; CDP1; COY1; Clox; GDDI; p100; p110; p200; CUTL1; GOLIM6; CDP/Cut; Cux/CDP; Nbla10317

基因 ID: 1523 | 基因类型: protein coding

关于 CUX1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:101,816,007-102,283,958 (from NCBI)

This gene has 23 transcripts (splice variants), 211 orthologues, 1 paralogue and is associated with 110 phenotypes. Ubiquitous expression in endometrium (RPKM 11.3), thyroid (RPKM 8.5) and 25 other tissues.

功能概要

由该基因编码的蛋白质是 DNA 结合蛋白同源域家族的成员。它可能调节基因表达、形态发生和分化，也可能在细胞周期进程中发挥作用。已经确定了几种编码不同亚型的可变剪接转录本变体。[RefSeq 提供，2011 年 2 月]

The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]

CUX1 基因产物(7)

mRNA Protein Name
NM_001202543.2 NP_001189472.1 Homeobox protein cut-like 1 isoform d
NM_001202544.3 NP_001189473.1 protein CASP isoform e
NM_001202545.3 NP_001189474.1 protein CASP isoform f
NM_001202546.3 NP_001189475.1 protein CASP isoform g
NM_001913.5 NP_001904.2 protein CASP isoform b
NM_181500.4 NP_852477.1 protein CASP isoform c
NM_181552.4 NP_853530.2 Homeobox protein cut-like 1 isoform a
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15656993 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15656993 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CUX1 蛋白结构

CUT

CUT: CUT domain (546 - 623)

CUT

CUT: CUT domain (936 - 1010)

CUT

CUT: CUT domain (1121 - 1199)

Homeobox

Homeobox: Homeobox domain (1245 - 1301)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1505 a.a.
蛋白主名 其他名称

protein CASP

Homeobox protein cut-like 1

CCAAT displacement protein

CUX1 抗体

目录号 产品名 应用 反应物种
HY-P83439 Protein CASP Antibody (YA3184) WB, ICC/IF, IP Human, Mouse, Rat

关联疾病

疾病名称 别名
Global Developmental Delay With Or Without Impaired Intellectual Development

GDDI
Autosomal Dominant Non-Syndromic Intellectual Disability
Leiomyoma

Leiomyomatous Neoplasm

Leiomyomatous Tumor

Leiomyomas

Fibroid Tumor

Uterine Fibroids
Leiomyoma, Uterine

Uterine Leiomyoma

Uterine Fibroid

Uterine Fibroids

Plexiform Leiomyoma

UL

Leiomyoma Of Corpus Uteri

Uterus Fibroma
Thyroid Gland Cancer

Thyroid Gland Carcinoma

Malignant Neoplasm Of Thyroid Gland

Malignant Tumour Of Thyroid Gland

Thyroid Neoplasm

Thyroid Neoplasms

Neoplasm Of Thyroid Gland

Thyroid Gland Neoplasm

Head And Neck Cancer, Thyroid

Neoplasm Of The Thyroid Gland

Cancer Of The Thyroid

Primary Malignant Neoplasm Of Thyroglossal Duct

Malignant Neoplasm Of Thyroglossal Duct

Primary Malignant Neoplasm Of Thyroid Gland

Thyroglossal Duct Cancer

Toxic Goitre Malignant Tumour

Cancerous Goitre
Uterine Corpus Endometrial Carcinoma
Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities
Thyroid Gland Medullary Carcinoma

Medullary Thyroid Carcinoma

Medullary Carcinoma Of The Thyroid Gland

Ultimobranchial Thyroid Tumor

Ultimobranchial Thyroid Tumour

Thyroid Cancer, Medullary
Multiple Endocrine Neoplasia, Type Iib

Multiple Endocrine Neoplasia Type 2b

MEN2B

Wagenmann-Froboese Syndrome

Multiple Endocrine Neoplasia Iib

Mucosal Neuroma Syndrome

Multiple Endocrine Neoplasia, Type 3

Multiple Endocrine Neoplasia, Type 2b

Men Iib

Neuromata, Mucosal, With Endocrine Tumors

Multiple Endocrine Neoplasia, Type Iii, Formerly

Men3, Formerly

Men Type Iib

Men 2b

Multiple Endocrine Neoplasia Type 3

Multiple Neoplasia 2b

Neoplasia, Endocrine, Multiple, Type Iib
Periventricular Nodular Heterotopia

Periventricular Heterotopia

Pvnh

Familial Nodular Heterotopia

Heterotopia, Periventricular

Periventricular Heterotopia, X-Linked
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03369 CUX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19592 Cux1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26088 Cux1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CUX1 RGD RGD:620618
Macaca mulatta CUX1 VGNC VGNC:81298
Canis familiaris CUX1 VGNC VGNC:39738
Felis catus CUX1 VGNC VGNC:107752
Bos taurus CUX1 VGNC VGNC:27839
Mus musculus CUX1 MGD MGI:88568
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z