2. Gene
  3. LINGO2 - leucine rich repeat and Ig domain containing 2 Gene

LINGO2 - leucine rich repeat and Ig domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含富亮氨酸的重复序列和 Ig 结构域 2

种属: Homo sapiens

同用名: LERN3; LRRN6C

基因 ID: 158038 | 基因类型: protein coding

关于 LINGO2

Cytogenetic location: 9p21.2-p21.1 Genomic coordinates (GRCh38): 9:27,937,617-29,213,601 (from NCBI)

This gene has 9 transcripts (splice variants), 274 orthologues and 25 paralogues. Low expression observed in reference dataset.

功能概要

预计在突触组装的正调节上游或正调节内起作用。预计是膜的组成部分。预计在细胞外基质和细胞外空间中具有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LINGO2 基因产物(4)

mRNA Protein Name
NM_001258282.3 NP_001245211.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor
NM_001354574.2 NP_001341503.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor
NM_001354575.2 NP_001341504.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor
NM_152570.4 NP_689783.1 leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 precursor

LINGO2 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (27 - 56)

LRR_8

LRR_8: Leucine rich repeat (106 - 165)

LRR_1

LRR_1: Leucine Rich Repeat (275 - 296)

LRR_8

LRR_8: Leucine rich repeat (298 - 357)

I-set

I-set: Immunoglobulin I-set domain (415 - 500)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 606 a.a.
蛋白主名 其他名称

leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2

leucine rich repeat neuronal 6C

关联疾病

疾病名称 别名
Essential Tremor

Benign Essential Tremor

Familial Tremor

Hereditary Essential Tremor

Essential Hereditary Tremor

Shaky Hand Syndrome

Benign Essential Tremor Syndrome

Tremor Hereditary Essential

Essential Tremor, Susceptibility To

Tremor, Hereditary Essential
Tremor, Hereditary Essential, 5

ETM5

Essential Tremor 5

Essential Tremor, Hereditary, 5

Hereditary Essential Tremor 5

Tremor, Hereditary Essential 5

Tremor, Essential Hereditary, Type 5
Tremor, Hereditary Essential, 4

ETM4

Essential Tremor 4

Essential Tremor, Hereditary, 4

Hereditary Essential Tremor 4

Tremor, Hereditary Essential 4

Tremor, Hereditary Essential, Type 4
Tremor, Hereditary Essential, 1

ETM1

Fet1

Essential Tremor 1

Tremor, Familial Essential, 1

Essential Tremor, Hereditary, 1

Hereditary Essential Tremor 1

Tremor Hereditary Essential, 1

Tremor Familial Essential, 1

Tremor, Hereditary Essential 1

Tremor, Essential Hereditary, Type 1
Ectodermal Dysplasia 14, Hair/Tooth Type With Or Without Hypohidrosis

ECTD14

Ectodermal Dysplasia 14

Ectn14
Motion Sickness

Airsickness

Carsickness

Seasickness

Travel Sickness

Riders' Vertigo
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07681 LINGO2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21146 Lingo2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27663 Lingo2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus LINGO2 VGNC VGNC:63237
Canis familiaris LINGO2 VGNC VGNC:42689
Rattus norvegicus LINGO2 RGD RGD:1310773
Bos taurus LINGO2 VGNC VGNC:30900
Mus musculus LINGO2 MGD MGI:2442298
Macaca mulatta LINGO2 VGNC VGNC:74095
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