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  3. Itpr3 - inositol 1,4,5-triphosphate receptor 3 Gene

Itpr3 - inositol 1,4,5-triphosphate receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: tf; Ip3r3; IP3R 3; Itpr-3

基因 ID: 16440 | 基因类型: protein coding

关于 Itpr3

功能概要

Enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity and phosphatidylinositol binding activity. Involved in calcium ion transport into cytosol. Acts upstream of or within several processes, including long-term synaptic potentiation; memory; and sensory perception of taste. Located in endoplasmic reticulum membrane; nucleolus; and nucleoplasm. Is expressed in several structures, including jaw; liver; sensory organ; skeleton; and spleen. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ITPR3 (inositol 1,4,5-trisphosphate receptor type 3). [provided by Alliance of Genome Resources, Apr 2022]

Itpr3 基因产物(1)

mRNA Protein Name
NM_080553.3 NP_542120.2 inositol 1,4,5-trisphosphate receptor type 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables inositol 1,4,5-trisphosphate-gated calcium channel activity IDA
IDA: 通过直接分析推断
9065779 MGI
enables intracellularly gated calcium channel activity IDA
IDA: 通过直接分析推断
20813840 MGI
enables phosphatidylinositol binding IDA
IDA: 通过直接分析推断
17327232 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16352659 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium ion transport IDA
IDA: 通过直接分析推断
15890645 MGI
acts upstream of or within long-term synaptic potentiation IMP
IMP: 通过突变表型推断
18417102 MGI
acts upstream of or within memory IMP
IMP: 通过突变表型推断
18417102 MGI
acts upstream of or within sensory perception of bitter taste IMP
IMP: 通过突变表型推断
17925404 MGI
acts upstream of or within sensory perception of sweet taste IMP
IMP: 通过突变表型推断
17925404 MGI
acts upstream of or within sensory perception of umami taste IMP
IMP: 通过突变表型推断
17925404 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16014380 MGI
located in cytoplasmic side of endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
21030605 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
16014380 MGI
located in nucleoplasm IDA
IDA: 通过直接分析推断
16014380 MGI
located in nucleus IDA
IDA: 通过直接分析推断
16014380 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

inositol 1,4,5-trisphosphate receptor type 3

IP3 receptor

insP3R3

type 3 InsP3 receptor

type 3 inositol 1,4,5-trisphosphate receptor

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06993 ITPR3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21604 Itpr3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itpr3 NCBI NCBI:3710
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