2. Gene
  3. Kpna2 - karyopherin (importin) alpha 2 Gene

Kpna2 - karyopherin (importin) alpha 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rch1; IPOA1; PTAC58; 2410044B12Rik

基因 ID: 16647 | 基因类型: protein coding

关于 Kpna2

功能概要

Enables DNA-binding transcription factor binding activity and nuclear import signal receptor activity. Acts upstream of or within entry of viral genome into host nucleus through nuclear pore complex via importin; positive regulation of viral life cycle; and protein import into nucleus. Located in cytoplasmic stress granule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human KPNA2 (karyopherin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Kpna2 基因产物(1)

mRNA Protein Name
NM_010655.3 NP_034785.1 importin subunit alpha-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
12695505 MGI
enables nuclear import signal receptor activity IDA
IDA: 通过直接分析推断
15689618 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10764582 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within entry of viral genome into host nucleus through nuclear pore complex via importin IMP
IMP: 通过突变表型推断
28189564 MGI
acts upstream of or within positive regulation of viral life cycle IMP
IMP: 通过突变表型推断
28189564 MGI
involved in postsynapse to nucleus signaling pathway IDA
IDA: 通过直接分析推断
15603742 MGI
involved in postsynapse to nucleus signaling pathway IMP
IMP: 通过突变表型推断
15603742 MGI
acts upstream of or within protein import into nucleus IDA
IDA: 通过直接分析推断
15689618 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
27430620 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15603742 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
15603742 MGI
is active in postsynaptic density IDA
IDA: 通过直接分析推断
15603742 MGI
is active in postsynaptic density IEP
IEP: 通过表达模式推断
15603742 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

importin subunit alpha-1

RAG cohort protein 1

SRP1-alpha

importin alpha 1

importin alpha P1

importin subunit alpha-2

karyopherin subunit alpha-2

m-importin-alpha-P1

pendulin

pore targeting complex 58 kDa subunit

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07416 KPNA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17914 Kpna2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24383 Kpna2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kpna2 NCBI NCBI:3838
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