2. Gene
  3. Krt18 - keratin 18 Gene

Krt18 - keratin 18 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: K18; CK18; Krt1-18

基因 ID: 16668 | 基因类型: protein coding

关于 Krt18

功能概要

Predicted to enable scaffold protein binding activity. Acts upstream of or within extrinsic apoptotic signaling pathway; hepatocyte apoptotic process; and tumor necrosis factor-mediated signaling pathway. Located in cell periphery and keratin filament. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT18 (keratin 18). [provided by Alliance of Genome Resources, Apr 2022]

Krt18 基因产物(1)

mRNA Protein Name
NM_010664.2 NP_034794.2 keratin, type I cytoskeletal 18
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10747083 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within extrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
10747083 MGI
acts upstream of or within hepatocyte apoptotic process IMP
IMP: 通过突变表型推断
10747083 MGI
acts upstream of or within tumor necrosis factor-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
10747083 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell periphery IDA
IDA: 通过直接分析推断
23284756 MGI
located in intermediate filament IDA
IDA: 通过直接分析推断
10747083 MGI
located in keratin filament IDA
IDA: 通过直接分析推断
21930775 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

keratin, type I cytoskeletal 18

cytokeratin endo B

cytokeratin-18

keratin D

keratin complex 1, acidic, gene 18

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07441 KRT18 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19704 Krt18 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26199 Krt18 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt18 NCBI NCBI:3875
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